价格:0.00/KG
品牌:南箭
起订:25KG
供应:9999KG
发货:3天内
信息标签:螺内酯,供应,化工,医药中间体

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螺内酯
螺内酯
螺内酯

螺内酯

产品类别： 利尿类原料药
质量标准： CP/EP/USP/BP
产品规格： 10Kg/桶

【品 名】螺内酯
【英 文 名】Spironolactone
【化 学 名】17β-羟基-3-氧-7α-(乙酰硫基)-17α-孕甾-4-烯-21-羧酸γ-内酯
【类 别】利尿类原料药
【规 格】10Kg/桶
【标 准】CP/EP/USP/BP


【性 状】 本品为白色或类白色的细微结晶性粉末；有轻微硫醇臭。
【鉴 别】 呈阳性反应。
【熔 点】 203℃~209℃，熔融时同时分解。
【比 旋 度】 -33?~ -37?。
【结晶细度】 10μm以下的结晶≥90％
【巯基化合物】消耗碘滴定液（0.005mol/L）不得过0.10ml。
【有关物质】 ≤1.0%。
【干燥失重】 ≤0.5%。
【含 量】 以干品计算含C24H32O4S应为97.0%~103.0%。
【贮 藏】 密封保存。

Spironolactone
Prodcut name: Spironolactone
Synonym: Aldactone;Antisterone;spirolactone;7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta- carbolactone
CAS Registry Number: 52-01-7
Assay: 97.0%~103.0%
Packaging: 1kg/foil bag
Molecular Formula: C24H32O4S
Molecular Weight: 416.5735
Appearance: White or almost white fine crystalline powder;Slightly bitter taste, odourless or slightly mercaptan odor.Insoluble in water, soluble in ethanol, soluble in benzene or ethyl acetate.
Usage: Spironolactone is competitive inhibition of aldosterone drugs, drug itself is not active, role is diuresis and endogenous competitive aldosterone antagonist and happen, belongs to the potassium diuretics.

It is a synthetic, steroidal antimineralocorticoid and antiandrogen that also has some weak progestogen properties, as well as some indirect estrogen and glucocorticoid effects. It is used primarily as a diuretic and antihypertensive, but may also be employed for the purpose of reducing elevated or unwanted androgen activity in the body.It acts predominantly as an antagonist of the mineralocorticoid (or aldosterone) and androgen receptors, and in relation to its antimineralocorticoid effects, belongs to a class of pharmaceutical drugs known as potassium-sparing diuretics.


Spironolactone (CAS: 52-01-7):