研究复杂的细胞和组织，及其信号传导与调控可不是件容易事。而模拟细胞或组织环境，建立**接近体内天然条件的实验系统同样困难。这就是3D细胞培养所面临的挑战，3D培养系统旨在更好的模拟细胞的体内生长环境，为其创造更天然的家。近来越来越多的证据表明，3D细胞培养系统比传统2D培养系统更贴近体内的生理条件。也许3D培养系统的**价值在于，其更接近体内环境的系统能够有效的辅助药物研发。“3D细胞培养的主要优势在于，能够在研究早期的体外实验中模拟细胞在体内的行为，”。“传统2D细胞培养往往无法了解细胞在组织内的功能和应答反应，结果可能导致以2D细胞培养为基础的药物或生物学研究出现偏颇，并且也难以预测药物在体内的效果。而3D细胞培养可以为研究者们提供药物等更真实的早期信息，从而降低像市场推出新药的研究成本。众多的科研工作者一直在寻找简单方便**天然的3D细胞培养工具？？？？？？？？

The Bio-Assembler™ System

The Bio-Assembler™ system cultures cells in three-dimensions by magnetic levitation. The Bio-Assembler™uses nanoparticle-based Nanoshuttle-PL solution to deliver magnetic nanoparticles to cells. Magnetic drives then levitate cells to create the 3D cell growth environment. Using the Bio-Assembler™ is as easy as performing standard monolayer (2D) culture. Preparation time and cell manipulation requirements are equivalent to 2D culture.

Advantages of n3D’s 3-Dimensional Cell Culturing System:

·         Rapid formation of 3D structures and cell-cell interactions

·         More accurate representation of in vivo tissue

·         Compatibility with virtually any cell type including primary and stem cells

·         Compatibility with any media type, standard culturing protocols, and diagnostic techniques

·         3D co-culturing capabilities

·         Unique capability for moving and shaping tissue, applicable to invasion studies and tissue engineering

As Simple as 2D

There are only two simple additional steps that differentiate the Bio-Assembler™ from 2D cell culturing: