英文名称  Anti-RAB3GAP1

中文名称  RAB3-GTP酶激活蛋白催化亚单位1抗体

别       名  DKFZp434A012; KIAA0066; P130; Rab3 GAP; Rab3 GAP p130; RAB3 GTPase activating protein 130 kDa subunit; Rab3 GTPase activating protein catalytic subunit; RAB3GAP; RAB3GAP130; WARBM1; RB3GP_HUMAN.

研究领域 细胞生物    

分 子 量 110kDa

性    状  Lyophilized or Liquid

浓    度  1mg/1ml

亚    型  IgG

Anti-RAB3GAP1抗体,RAB3-GTP酶激活蛋白催化亚单位1抗体产品介绍：Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab 3 GAP p130, also known as Rab3 GTPase-activating protein catalytic subunit, is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab 3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP, and is required for normal eye and brain development. Defects in Rab 3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1). WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab 3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters. Existing as two alternatively spliced isoforms, the Rab 3 GAP p130 gene is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish and fruit fly, and maps to human chromosome 2q21.3.

 

抗体来源：本公司抗体有兔来源和鼠来源等

克隆类型：兔来源为多抗，鼠来源为单抗

产品类型：一抗

保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

连续使用时4°C存储，保质期六个月补体C1qα链多肽抗体长期存储时建议分装为10ul以上小包装-20°C存储，并避免反复冻融，保质期一年。